This church was completed during the 1250s, then almost completely rebuilt using Baroque designs around 1627.
A fresco by Domenico Ghirlandaio (circa 1472) above the second alter on the right side depicts Madonna della Misericordia, protector of the Vespucci family. The young face of Amerigo Vespucci, a navigator from Florence who famously gave the American continent his name, is said to appear between the Madonna and the old man.
Ghirlandaio’s St Jerome portrait sits in the nave while his incredible Last Supper appears on the wall of the refectory (reached via the cloister). Also in the nave is Botticelli‘s San Augustin.